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Senior Research Sister / Charge Nurse, Cystic Fibrosis – Phase 1

Band 7

Main area
Research & Development
Band 7
Fixed term: 2 years
Full time - 37.5 hours per week
Job ref
Southampton General Hospital
£38,890 - £44,503 per annum pro rata
Salary period
20/04/2021 23:59
Interview date

Job overview

We are delighted to introduce this new band 7 Senior Research Sister / Charge Nurse CF & ATIMP role within our Research Team at the University Hospital Southampton NHS Foundation Trust (UHS). This two year fixed term role is part of a national pilot programme in collaboration with the Clinical Trials Accelerator Platform (CTAP) for Phase 1 Cystic Fibrosis Research. 


UHS is one of the UK's most successful healthcare organisations. Clinical Research is a core activity of the Trust and our Clinical Research Facility provides a comfortable, safe, environment for participation in clinical trials, embedded in the heart of one of the UK's largest NHS teaching hospitals. There are approx 300 Research Nurses, AHPs, Midwives and Clinical Trials Assistants, working together across the Trust, within our award winning teams to bring exciting research opportunities to UHS for the benefit of our patients and for the future of healthcare.

Main duties of the job

You can read an overview of the main duties of the role in the section below: Job Description and Main Responsibilities.

To understand the role in more detail please read the full job description and person specification documents attached.

Working for our organisation

As one of the largest acute teaching Trusts in England, we offer learning and development opportunities to help you achieve the career you aspire to. UHS is rated ‘Good’ by the CQC and in the latest national NHS Staff Survey, we were in the top 10 acute trusts for staff engagement and for staff recommending the hospital as a place to work or receive care. 

We support flexible working and will consider requests taking into account the needs of the service. UHS employees are able to access a range of NHS discounts, are entitled to a minimum of 35 days paid holiday (pro rata), and we offer a generous pension scheme.

Southampton is an attractive place to live and work situated on the south coast, with an international airport and direct trains to London. The New Forest National Park and beaches of the Jurassic coast are also right on our doorstep. The city offers living costs 20% lower than London and 14 schools rated outstanding by Ofsted.

Detailed job description and main responsibilities

The post-holder can expect a detailed induction and training package specific to their needs and experience. Our dedicated education team and supportive leadership structure ensures that all our staff have the skills and knowledge to care for their patients and undertake research to the highest standards. 

We are able to develop fantastic relationships with our patients and their families. We are in a very fortunate position to be able to build trust and to support our patients with excellent follow-up and continuity of care.


  • Responsible for the day-to-day management of the CF and ATIMP Research Nursing Team ensuring appropriate cover and skill mix for smooth running of research projects.
  • Liaise with the Principal Investigators (PIs), allocate research projects to research nurses/AHPs, using professional judgement to assess workload and nursing capacity and ensure studies are delivered to time and targets.
  • Provide professional leadership and support at departmental level and collaborate to enhance clinical practice and strategy.
  • The nature of early phase and ATIMP studies means compliance to GCP and phase 1 / ATIMP governance requirements are paramount to patient safety and research outcomes. The post holder will disseminate this crucial and expert knowledge in the form of tailored training and mentorship activities to support other CF centres and staff to become phase 1 ready.


We are looking for an experienced research nurse to lead our expanding portfolio of Phase 1 Cystic Fibrosis and ATIMP Research.

The following skills and experience are required for this post:

  • Respiratory nursing experience, respiratory clinical skills and knowledge of Cystic Fibrosis .
  • Expert research skills and knowledge in local and national early phase and ATIMP regulations and approvals, including site specific phase 1 and QA processes.
  • Excellent communication and interpersonal skills including mentorship and teaching experience.
  • Advanced understanding of Microsoft Applications e.g. Word and Excel
  • Exceptional attention to detail and organisation skills
  • The ability to lead and motivate a team to deliver excellent clinical care and increase early phase research activity  


Interviews will be held on Friday, 30 April 2021

If you’re interested in applying for this role, we’d encourage you to get in touch using the contact information at the bottom of this advert with any questions or if you would like to arrange an informal visit. Alternatively, if you’re ready to apply, please follow the link below to complete an application.

Person specification


Essential criteria
  • Registered Nurse or AHP on relevant part of the professional register (NMC HCPC)
  • Evidence of on-going professional development.
  • Experience of teaching and mentorship
  • Educated to Post Graduate Degree level or equivalent experience
Desirable criteria
  • Recognised qualification in teaching and mentorship
  • Recognised qualification in relevant speciality


Essential criteria
  • Experience of working with patients at a senior level.
  • Clinical Research experience including early phase / Ph1
  • Relevant speciality experience
  • Knowledge of current issues within acute health care
  • Management experience
  • NHS experience or equivalent
  • Knowledge of Research Governance Framework (RGF), International Conference on Harmonisation/Good Clinical Practice (ICH/GCP)
  • Logical and consistent work and career pattern
Desirable criteria
  • Research coordinator experience


Essential criteria
  • Leadership skills- evidence of ability to help/support junior staff
  • Demonstrates clarity and breadth in use of verbal and written communications in relation to our patient group
  • Ability to work independently assessing and treating CF patients participating in research
  • Able to use initiative
  • Able to prioritise and deliver agreed objectives
  • Understanding of personal accountability. PC literate
  • To be able to read and understand complex research protocols
Desirable criteria
  • Experience of budgetary control
  • Experience of venesection
  • Experience of cannulation

Special requirements

Essential criteria
  • Flexible working arrangements
  • Able to work occasional unsocial hours (evening and weekend)
  • Proven ability to manage change
  • Car driver, with full driving licence, or ability to travel between hospital sites or for necessary patient visits


Essential criteria
  • Able to demonstrate behaviours that meet the Trust Values Patients First
  • Able to demonstrate behaviours that meet the Trust Values Always Improving
  • Able to demonstrate behaviours that meet the Trust Values Working Together
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Applicant requirements

You must have appropriate UK professional registration.

This post is subject to the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975 (Amendment) (England and Wales) Order 2020 and it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service.

Documents to download

Apply online now

Further details / informal visits contact

Lisa Berry
Job title
Matron - Research & Development
Email address
Telephone number
07584 441034

If you have problems applying, contact

If you have problems with the
online application form please contact
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01629 690826